Identification of a Human VPF/VEGF 3′ Untranslated Region Mediating Hypoxia-induced mRNA Stability
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چکیده
منابع مشابه
Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability.
Hypoxia is a prominent feature of malignant tumors that are characterized by angiogenesis and vascular hyperpermeability. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) has been shown to be up-regulated in the vicinity of necrotic tumor areas, and hypoxia potently induces VPF/VEGF expression in several tumor cell lines in vitro. Here we report that hypoxia-induced VP...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 1998
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.9.2.469